Nonlinear capacitance and electrochemical response of ionic liquid-ionic polymers

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98712/1/JApplPhys_109_084901.pd

Boundary layer charge dynamics in ionic liquid-ionic polymer transducers

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98705/1/JApplPhys_109_014909.pd

Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice.

Mutations in SLURP1 cause mal de Meleda, a rare palmoplantar keratoderma (PPK). SLURP1 is a secreted protein that is expressed highly in keratinocytes but has also been identified elsewhere (e.g., spinal cord neurons). Here, we examined Slurp1-deficient mice (Slurp1(-/-)) created by replacing exon 2 with β-gal and neo cassettes. Slurp1(-/-) mice developed severe PPK characterized by increased keratinocyte proliferation, an accumulation of lipid droplets in the stratum corneum, and a water barrier defect. In addition, Slurp1(-/-) mice exhibited reduced adiposity, protection from obesity on a high-fat diet, low plasma lipid levels, and a neuromuscular abnormality (hind-limb clasping). Initially, it was unclear whether the metabolic and neuromuscular phenotypes were due to Slurp1 deficiency, because we found that the targeted Slurp1 mutation reduced the expression of several neighboring genes (e.g., Slurp2, Lypd2). We therefore created a new line of knockout mice (Slurp1X(-/-) mice) with a simple nonsense mutation in exon 2. The Slurp1X mutation did not reduce the expression of adjacent genes, but Slurp1X(-/-) mice exhibited all of the phenotypes observed in the original line of knockout mice. Thus, Slurp1 deficiency in mice elicits metabolic and neuromuscular abnormalities in addition to PPK

Transnational and diasporic youth identities: exploring conceptual themes and future research agendas

This special issue brings together multidisciplinary and international perspectives on the importance of diasporic and transnational networks for the formation of ethnic identity by migrant youths. Within the context of this issue migrant youths refer to young people (aged 16–35 years) who are themselves migrants or are children and grandchildren of migrants. Our attention to the transnational and diasporic identities of migrant youths is in direct response to policy debates and migration scholarship in this area, which in recent times have focused on the supposed crisis of minority ethnic youths and their perceived marginalisation and social exclusion from a wider society. The special issue broadens the parameters of this debate by exploring not how transnational migrant youths are but more interestingly, we believe, what it means for them to have grown up in a transnational social field. In the special issue rather than simply addressing identity outcomes, we want to emphasise identity processes. This is because we are more interested in understanding the ways the migrant youths are ‘doing transnationalism’ and also through this process ‘doing identity’ (including intersected racial, ethnic, gender, class and sexual identities)

Polish children in Norway : between national discourses of belonging and everyday experiences of life abroad

This chapter examines dimensions of self-identification among Polish migrant children in Norway. The arguments are situated within childhood studies and take into account the novel framings of children in mobility/migration scholarship, as well as articularities of Polish context Stemming from the TRANSFAM research project (2013-2016), this work “gives children a voice” through a qualitative research methodology. The study illuminates those national, transnational and global elements that are paramount for daily life family practices and featured in children’s narratives. The paper focuses on the importance of socializing agents (family, peer groups, culture) for the constructions of belonging. It concludes with arguments for acknowledging the contemporary hybrid and relational identities of children who grow up transnationally between Norway and Poland

Gastrointestinal decontamination in the acutely poisoned patient

ObjectiveTo define the role of gastrointestinal (GI) decontamination of the poisoned patient.Data sourcesA computer-based PubMed/MEDLINE search of the literature on GI decontamination in the poisoned patient with cross referencing of sources.Study selection and data extractionClinical, animal and in vitro studies were reviewed for clinical relevance to GI decontamination of the poisoned patient.Data synthesisThe literature suggests that previously, widely used, aggressive approaches including the use of ipecac syrup, gastric lavage, and cathartics are now rarely recommended. Whole bowel irrigation is still often recommended for slow-release drugs, metals, and patients who "pack" or "stuff" foreign bodies filled with drugs of abuse, but with little quality data to support it. Activated charcoal (AC), single or multiple doses, was also a previous mainstay of GI decontamination, but the utility of AC is now recognized to be limited and more time dependent than previously practiced. These recommendations have resulted in several treatment guidelines that are mostly based on retrospective analysis, animal studies or small case series, and rarely based on randomized clinical trials.ConclusionsThe current literature supports limited use of GI decontamination of the poisoned patient

Caribbean second-generation return migration: transnational family relationships with ‘left-behind’ kin in Britain

There has been increasing research interest in second-generation return migration to the Caribbean. However, little is known or understood about these returnees’ relationships with ‘left-behind’ kin in Britain. Drawing on qualitative data, the paper examines this issue in order to provide new insights into existing research on second-generation return migration. Special attention is given to understanding the reasons why these backward links are important to the return migrants, and the variety of ways that individuals maintain, negotiate and curtail relational ties with specific family members ‘left behind’ in Britain. Social capital theory, particularly the notion of bonding social capital, is used to consider the resources and support provided by left-behind kin